Organoid·Protocol·Atlas
Explore Heatmap Consensus Ask Dashboard Protocols Reagents llms.txt GitHub
ORGANOID PROTOCOL ATLAS Explore Figures Heatmap Consensus Dashboard Ask llms.txt Source
Public CC subset - evidence-grounded

Organoid Protocol Atlas

A license-safe public slice of the organoid protocol corpus, turned into structured, queryable protocol records: source cells, matrix, base media, and signaling cocktail rows with DOI-linked evidence snippets. The full local pipeline tracks the larger verified corpus; this hosted build exposes the public CC subset without redistributing full methods text.

CC paper subset-> short evidence snippets-> public protocol KG-> compare / query
582
public protocols
5458
public rows
25
organoid systems
CC
public license filter
0
full-text bodies
1
agent guide at /llms.txt

Browse protocols ->

One public recipe card per paper: cells, matrix, media, signaling cocktail with concentrations and evidence snippets. Faceted by organoid type, source cell, license.

Morphogen grammar ->

The signature view: every canonical signaling factor by every public organoid system, as a heatmap. See which morphogens recur and which are lineage-specific; figure-confirmed cells are marked when available.

Consensus recipes ->

The canonical recipe per organoid system: each factor's usage frequency across that type's public protocols, core cocktail vs variable additions, with modal doses. Computed, not asserted.

Ask the Atlas ->

Natural-language questions retrieve grounded rows from the public knowledge graph. If a local model is attached, it synthesizes answers; otherwise the evidence rows are shown.

Track one reagent ->

See how a single factor, such as CHIR99021, EGF, or R-spondin, is used and dosed across every public protocol that includes it.

Explore & search ->

A fast, bespoke search over every extracted reagent — filter by organoid type, kind, role, and grounding; each result links to its evidence and source DOI.

Grounding coverage ->

How much of each public protocol's cocktail is evidence-grounded. The honest quality signal that drives where to improve next.

Gold candidates ->

Public rows can be filtered for benchmark candidates, while human-verified gold evaluation remains a gated local workflow.

TRAPI / Biolink KG ->

The committed KGX graph is live-queryable via TRAPI 1.5: POST /trapi/query with a single-hop Biolink message, or GET /trapi/meta_knowledge_graph for the schema. Every node carries an SRI-resolved CURIE.

Analytics dashboard ->

Corpus-level metrics in one page: grounding coverage, quality tier distribution, MIOR completeness, top organoid systems, and assay clusters — all from committed, reproducible pipeline artifacts.

Open source (MIT) - extraction runs locally - short citation snippets only, full text not redistributed - llms.txt - github.com/rhowardstone/organoid-protocol-atlas
Powered by Datasette · Data license: MIT · Data source: PMC Open Access + author-manuscript corpus (per-row license in the data)